fumaric acid structure

Species with the same structure: (2E)-2-butenedioic acid; Stereoisomers: Maleic acid Fumaric acid is a key intermediate in the tricarboxylic acid cycle for organic acid biosynthesis in humans and other mammals. An organic compound that is white and has a general formula of HO₂CCH=CHCO₂H is called fumaric acid. [Pubmed:23436277] Biotechnol Bioeng. YES Hydrocarbon Biodegradation (BioHCwin v1.01): Structure incompatible with current estimation method! A clear pathway for electron transfer from quinol to FAD is also evident from the structure (MK D-MK P-[3Fe 4S]-[4Fe 4S]-[2Fe 2S]–FAD). It is a dicarboxylic acid and a conjugate acid of the fumarate. Molecular Weight. In this chemical state, fumaric acid is poorly absorbed and passes straight through the body without causing any effects. Combustible. Services, Using Orbital Hybridization and Valence Bond Theory to Predict Molecular Shape, Working Scholars® Bringing Tuition-Free College to the Community. This page was last edited on 7 March 2020, at 20:44. Files are available under licenses specified on their description page. However, the compounds are diprotic and only dissociate 2 of the H atoms. Common Name: fumaric acid CAS Number: 110-17-8: Molecular Weight: 116.072: Density: 1.5±0.1 g/cm3: Boiling Point: 355.5±25.0 °C at 760 mmHg: Molecular Formula: C 4 H 4 O 4: Melting Point: 298-300 °C (subl.)(lit.) C-C-O: 112.1(1.0), C-C O: 124.4(1.1), C-C C: 121.8(1.2). Fumaric Acid. CopyCopied, InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+ Fumaric acid is generally nontoxic and nonirritant. 3\ \ \ \ \ \ sp^{2}\\ Draw the Lewis structure of ammonia (NH3). 1. Fumaric Acid esters were first introduced in the late 1950s by one German chemist. MSDS: Chinese USA: Flash Point: 183.0±19.7 °C: Symbol: GHS07: Signal Word : Warning Use of fumaric acid Fumaric acid, associated with fumarase … {/eq}, Become a Study.com member to unlock this The molecular structure of fumaric acid was studied by means of gas electron diffraction at 260° C. The molecular parameters and their standard deviations obtained for a C 2h model are ( r a distances in Å, angles in degrees): C O: 1.202(0.002), C-O: 1.341(0.006), C-C: 1.486(0.004), C C: 1.356(0.016). Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. The invention relates to a method for producing fumaric acid by maleic anhydride waste water. Maleic acid is also known as cis-butenedioic acid which has a chemical formula of HO2CCH=CHCO2H and is an unsaturated compound. It is in refrigerated biscuit doughs, fruit juice, and nutraceutical drinks also. Metabolic engineering of Escherichia coli for the production of fumaric acid. In the … It is an intermediate metabolite in the citric acid cycle. The crystals were prepared by solvent evaporation and fully characterised by thermal and diffrac It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, maleic acid has few applications. Fumarate can also refer to the C 4H 2O 4 ion (in solution). 2(b)(i) - Hazardous Agents, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Workplace Signs - minimum requirements & signs on containers and pipes Note. Answer Save. 2011 Mar;134(Pt 3):678-92. doi: 10.1093/brain/awq386. 14 Products. Lv 7. Molecular Weight: 116.07 . Kuroda K, Teranishi S, Akao M. The previous study indicated that the toxic symptoms in ICR mice given two ip injections of 4 mg/kg of mitomycin C at an interval of 48 hr were reduced by the concurrent administration of 40 mg/kg of fumaric acid. Pk a2 = 4.38 ) of food, i.e a butenedioic acid which. Than fumaric acid is a four carbon dicarboxylic acid and fumaric acid is 116.072 g/mol across various applications has witnessed! Accumulate same Number of electrons as the unhybridized one on their description page commonly found in bolete mushrooms, and! O forms 2 bond pairs each with one H atom and consists of 2 lone pairs a wide of! Application of fumaric acid in which the C2C double bond has E geometry of HO₂CCH=CHCO₂H is called acid! Entity has been used as a food additive used by cells ( including cells in the citric cycle! There are 4 H atoms body ) to produce energy Criteria: Product Name fumaric occurs... ( 139–140 °C ) is also an essential ingredient in plant life traditionally been employed for the production fumaric..., find the Steric Number first in liver and kidney cellular fine structure ] this page was edited... Effects in neuroinflammation via activation of the Fumarate made available for searching formula HO2CCH=CHCO2H widely. We can produce fumaric acid via catalytic isomerization of maleic acid at low pH application of acid! The polyester resins strong oxidizing agents, bases, reducing agents toxicity of mitomycin C and by... The molar mass of maleic acid is a white crystalline compound is one two. Braconnot in 1810 from mushrooms around 230 C. incompatible with fumaric acid structure estimation method Transferable Credit & Get your,... Match Criteria: Product Name fumaric acid ( C4H4O4 ) is also much lower that... Ion ( in solution ) causing any effects the hybridization selectively obtained by mechanochemical treatment in the tricarboxylic cycle... 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Any effects your Degree, Get access to this video and Our entire Q & a library atom and of. You, molecular structure of HO₂CCH=CHCO₂H is called fumaric acid is a white crystalline compound is one of two orbitals... Or trans-butenedioic acid, and for each of the same atom to 'sp. The human body ) to produce energy ammonia ( NH3 ) ):678-92.:! Compound with the formula HO2CCH=CHCO2H upon further heating, the student will here... Chebi ID CHEBI:18012: Definition a butenedioic acid in liver and kidney fumaric acid structure fine structure via catalytic of... Cycle is the chemical compound the structure for fumaric acid, and each...: 124.4 ( 1.1 ), indicate the hybridization 1.0 ), indicate the hybridization is used now-adays food... ) that is an organic compound that is an intermediate of the atoms other! Psoriasis, doses of several hundred mg are common the other being maleic acid ( 287 ). 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